OSAKA SANGYO UNIVERSITY's
Faculty of Sport and Health Sciences
Department of Sport and Health Sciences

Professor

Tadayoshi Miyamoto


Career

  1. Osaka University School of Health and Sports Sci./Div. of Motor Behavioral Ed, Research Associate 1997/06/01-2000/03/31
  2. National Cardiovascular Research Institute Dept. of Cardiovascular Dynamics Research Fellow 2000/04/01-2007/03/31
  3. Morinomiya University of Medical Sciences Faculty of Health Sciences Professor 2007/04/01-2011/03/31
  4. National Cerebral and Cardiovascular Center Research Institute Department of Cardiovascular Dynamics Visiting scholar 2007/04/01-Present
  5. Morinomiya University of Medical Sciences Graduate School of Health Sciences Professor 2011/04/01-2019/03/31
  6. Osaka City University Research Center for Urban Health and Sports Visiting Professor 2016/04/01-Present
  7. OSAKA SANGYO UNIVERSITY Faculty of Sport and Health Sciences 教授 2019/04/01-Present
  8. OSAKA SANGYO UNIVERSITY Graduate School of Human Environment Professor 2019/04/01-Present

Academic background

  1. 大阪教育大学 1990/03 Graduated
  2. 大阪教育大学大学院 Master course 1992/03 Completed
  3. Osaka City University Doctor course 1995/03 Completed

Academic degrees

  1. 博士(学術) 大阪市立大学 1995/03

Licenses and qualifications

  1. 高等学校教諭専修免許保健体育 1992/03 大阪府教育委員会
  2. 中学校教諭専修免許保健体育 1992/03 大阪府教育委員会

Current state of research and teaching activities

Cardio-respiratory control mechanisms
Cardio-respiratory control mechanisms

Research theme
Elucidation of control mechanism of respiratory circulatory regulation system by integrated framework and its applied research.

Research activity
Many negative feedback control systems exist to maintain homeostasis in the living body. It is well known that the respiratory chemoreflex system and baroreflex system are essential negative feedback systems to maintain blood gas, pH and blood pressure homeostasis.

Many mammals, including humans, are considered to have acquired excellent physiological functions through evolution and adaptation in diverse environments.

At the start of exercise, in response to the increase of active muscle metabolism, a mechanism to control the respiratory circulatory system accurately and quickly is required to supply oxygen without time delay.

In the past, exercise physiology has been studied for over 100 years. During exercise, there is a variety of control such as modulation by direct neural signal input from the center (central command; feed forward control), modulation by mechanoreceptor reflex and metabolic receptor reflex from active muscle, and feedback regulation by respiratory chemoreflex and arterial baroreflex. It has been clarified that a control mechanism exists.

During exercise, oxygen and carbon dioxide in the blood, hydrogen ion concentration (PO2, PCO2, pH), and blood pressure homeostasis are maintained. This maintenance mechanism is considered to be established by sharing many functions rationally and purposefully while repeating many interactions. Therefore, it is thought that a very flexible and sophisticated control mechanism works every moment in the process of determining the dynamics of the respiratory circulatory system response during exercise.

In my laboratory, in order to understand the operating principle of the negative feedback control system during exercise, we use linear system analysis widely used in the field of engineering to target people ranging from athletes to patients. We conduct basic and applied research for small animals from clinical research.

In the laboratory, we comprehensively understand the adaptation mechanism to exercise, and, through these studies, we approach the essence of complex life systems, and have made research results to use them in the practice of sports science, basics and clinical medicine. I believe.

In 2002, the completion declaration of "Human Genome Project" was reported. From now on, we think that the flow of physiological research as "system biology" from elucidation of biological functions and mechanisms from the viewpoint of "gene to individual" or "molecule to human" will be the trend of post-genome research You Among them, I would like to continue to emphasize the importance and attractiveness of systematically understanding and studying the dynamic and complex responses of the respiratory circulatory system to exercise.

Research Areas

  1. Sports science
  2. Applied health science
  3. Neurophysiology/General neuroscience
  4. General physiology
  5. Environmental physiology (including physical medicine and nutritional physiology)

Research keywords

  1. Physiology
  2. System analysis
  3. Sport Sciences
  4. Training
  5. Learning
  6. Higher brain center
  7. 心不全
  8. Respiratory abnormality
  9. Adaptation

Subject of research

  1. System physiology of cardio-respiratory control in man An integrative approach to exercise physiology using systems analysis and mathematical simulation 1994/04/01-Present

Bibliography

  1. 運動と循環、呼吸 第10巻1号「言語聴覚士に必要な運動生理学 ディサースリア臨床研究 2020/12
  2. 「体育の科学」 68巻9号「運動時の循環調節の探索と新しい発見を知る」 杏林書院 2018/09
  3. 運動生理学分野における呼吸循環研究の最前「運動時の呼吸調節」「循環制御」8月号 日本循環制御医学会 2018/08
  4. The Lung perspectives『特集 呼吸器の救急救命治療』Vol.20 No.1,冬号 MEDICAL REVIEW社 2012
  5. 身体運動と呼吸・循環機能  真興交易(株)医書出版部 2012/08

Papers

  1. Research paper (scientific journal) Integrated respiratory chemoreflex-mediated regulation of cerebral blood flow in hypoxia: Implications for oxygen delivery and acute mountain sickness Exp Physiol. 106/ 9, 1922-1938 2021/09 10.1113/EP089660
  2. Research paper (scientific journal) Joint Closed-loop identification of baroreflex properties in the frequency domain. Frontiers in Neuroscience 2021/08/30 10.3389/fnins.2021.694512
  3. Research paper (scientific journal) Joint Exercise training intensity-dependent adaptive changes in the cardiorespiratory function. Japanese Society for Medical and Biological Engineering Proc 59, 621-623 2021/06
  4. Research paper (scientific journal) Joint Dynamic characteristics of cerebrovascular reactivity or ventilatory response to change in carbon dioxide Exp Physiol. 105/ 9, 1515-1523 2020/09 10.1113/EP088800
  5. Research paper (scientific journal) Joint Low frequency severe-intensity interval training markedly alters respiratory compensation point during incremental exercise in untrained male. Frontiers in Physiology 2020/09/04 10.3389/fphys.2020.01100

Research presentations

  1. Public discourse, seminar, tutorial, course, lecture and others 呼吸調節のシステム解析とその応用~生命現象の定量的理解に向けて~ 日本生体医工学会関西支部講演会 2021/12/04
  2. Oral presentation(general) 中心循環血液量の変化が呼吸化学調節フィードバック系に及ぼす影響 第76回日本体力医学会学術大会シンポジウム 2021/09/18
  3. Oral presentation(general) Effects of regional heat stimulation by moxibustion on cardiovascular responses. 第83回日本生体医工学会 2021/06
  4. Oral presentation(general) Exercise training intensity-dependent adaptive changes in the cardiorespiratory function. 第83回日本生体医工学会 2021/06
  5. Oral presentation(general) 大学男子バレーボール選手の起立負荷に対する循環調節機能 第30回関西臨床スポーツ医・科学研究会 2021/06

Prizes

  1. 第20回統合医療学会「IMJ2016 優秀ポスター賞」 2016/12
  2. 平成17年度 第2期 大阪大学 共通教育賞  「健康科学実習」 2005/04
  3. 第5回Neurocardiology Workshop奨励賞 心臓交感神経刺激は接合部前αアドレナリン作用を介して動的な迷走神経性心拍数調節を抑制しない 2004/07
  4. 第40回日本臨床生理学会優秀論文賞 Oxygen uptake kinetics under hypoxia and hyperoxia at the starting of and recovery phases of treadmill exercise 2003/10
  5. 第33回日本臨床生理学会優秀論文賞 Effects of treadmill walking in water on ventilatory response in obese subjects 1996/10

Alloted class

  1. スポーツ科学
  2. 運動科学
  3. スポーツ科学実習1・2
  4. 入門ゼミ1・2
  5. フィールド支援演習1・2

Social Contribution

  1. 大阪市立大学 都市健康・スポーツ研究センター 客員教授 2016/04/01-Present
  2. 国立循環器病研究センター研究所 客員研究員 2007/04/01-Present
  3. 日本循環制御医学会 評議員 2017/09-Present
  4. 日本体力医学会 評議員 2017/09-Present
  5. 日本体力医学会 近畿地方会 幹事 2018/04-Present

Memberships of academic societies

  1. 日本生体医工学会 2016/12-Present
  2. 日本循環制御医学会 2001/04-Present
  3. 日本循環器学会 2000/04-Present
  4. アメリカスポーツ医学会 1997/04-Present
  5. 運動生理学会 1990/04-Present

Unused input form4

  1. 最新トレーニング理論に基づく革新的運動プログラムのアスリートへの応用 18K10912 General 中原 英博 森ノ宮医療大学, 保健医療学部, 教授 2018 2020
  2. 呼吸循環代謝システムの長期トレーニング適応における順序発現機構の解明 15K01578 General 中原 英博 森ノ宮医療大学, 保健医療学部, 教授 2015 2017
  3. A comprehensive study on teacher training in medical and health science universities: 25350867 General 荻原 俊男 森ノ宮医療大学, 保健医療学部, その他 2013 2015
  4. 運動習慣が脳循環動態・脳循環調節機能に及ぼす影響:脳疾患予防の基礎的研究 24300237 General 小河 繁彦 東洋大学, 理工学部, 教授 2012 2014
  5. 脳卒中に伴う摂食嚥下障害発生機構の神経解剖学的解明 23592725 General 森谷 正之 森ノ宮医療大学, 保健医療学部, 教授 2011 2013

Research Projects (Competitive Research Funds)

  1. Science research expense 神経性・体液性調節メカニズムが運動時の末梢循環及び糖代謝機構に及ぼす影響 20K20622 挑戦的研究(開拓) Representative 宮本忠吉 2020/07/30-2023/03/31
  2. Science research expense 高位中枢の予測見込み的制御が激運動時の呼吸循環動態及び神経内分泌機能に及ぼす影響 16K13023 挑戦的萌芽研究 Representative 宮本 忠吉 2016/04/01-2019/03/31
  3. Science research expense Pathophysiological mechanism of exercise hyperventilation using a system analysis approach to integrated response in respiratory system 15H03101 基盤研究(B) General Representative 宮本 忠吉 2015/04/01-2019/03/31
  4. Science research expense Effect of Changes in Central Hemodynamics on the RespiratoryChemorelfex Feedback System Controlling Ventilation in Humans. 22500617 基盤研究(C) General Representative 宮本 忠吉 2010/04/01-2013/03/31
  5. Science research expense An integrative approach to exercise physiology using system sanalysis and mathematica simulation 19500574 基盤研究(C) General Representative 宮本 忠吉 2007/04/01-2009/03/31